Study Design Calculators Documentation

Each tool has an explination of what it does and the statistics behind it. Below you can find more in depth documentation that are not tied to a specific tool.

Power

Hypotheses
An overview of the types of hypotheses that you can use when performing a power and sample size calculation.
Margins
An overview of the margin parameter used in one-sided tests and tests of equivalence.
The Posterior Error Approach to Sample Size Determination
An explanation of the posterior error approach to sample size determination; a Bayesian approach to the topic.

Study Design

The Replicated Crossover Design for Testing Variabilities
An overview of the replicated crossover design for testing variability.
The Parallel Design with Replicates for Testing Variabilities
An overview of the replicated parallel design for testing variability.